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Rh Incompatibility Medications, Costs & Savings
Pharmacist insight
For hormonal medications, timing consistency is crucial for optimal effectiveness. I recommend setting a daily alarm as a reminder. Many generic oral contraceptives and hormone replacement therapies are bioequivalent to brand-name versions, offering the same protection at lower cost.
Angela C. Beverly, PharmD
About Rh Incompatibility
Rh incompatibility is a blood condition that can arise during pregnancy, potentially affecting a baby's health if not managed. It occurs when an Rh-negative mother carries an Rh-positive baby. Fortunately, effective treatments exist, and TheDrugClub helps ensure these essential medications are affordable, allowing families to focus on a healthy pregnancy without financial stress.
The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.
MedlinePlus overview of Rh Incompatibility
What is the Rh factor?
There are four major blood types: A, B, O, and AB. The types are based on substances found on your blood cells. Your blood type also has a positive or negative sign. This is called Rh factor, which is a protein. If your blood cells have this protein, you are Rh-positive. If you don't, you are Rh-negative.
Rh factor is inherited (passed down through families). Most people are Rh-positive, meaning they have the Rh factor. Rh-negative people don't have it. Being Rh-negative doesn't affect your health, but it can affect the health of your fetus if you are pregnant.
What is Rh incompatibility?
If you are pregnant and are Rh-negative and your fetus is Rh-positive, it's called Rh incompatibility. Blood from your fetus can cross into your bloodstream, especially during childbirth. If you're Rh-negative and your baby is Rh-positive, your body will react to the fetus's blood as a foreign substance. It will create antibodies (proteins) that can damage their red blood cells.
These antibodies usually don't cause problems during your first pregnancy. But Rh incompatibility may cause problems in later pregnancies if the fetus is Rh-positive. This is because the antibodies stay in your body once they have formed. During your next pregnancy, the antibodies can cross the placenta (the organ that grows in the uterus to provide oxygen and nutrients to the fetus) and attack the red blood cells of the fetus. Rh incompatibility can cause Rh disease, a serious condition that can cause a severe type of anemia.
How is Rh incompatibility diagnosed?
Your health care provider will order blood tests during your first trimester of pregnancy. This is often done at your first prenatal visit. These tests can check if you have Rh factor and if your body has made antibodies.
How is Rh incompatibility treated?
During your pregnancy, injections of a medicine called Rh immune globulin can keep your body from making Rh antibodies. It helps prevent the problems of Rh incompatibility.
After delivery, if your baby is born Rh-positive, you'll need another injection of the Rh immune globulin. But if you're Rh-negative and your baby is born Rh-negative, you don't need any other treatment.
If treatment is needed for the baby, it may include phototherapy (light therapy) if treatment is needed for jaundice, supplements to help the body make red blood cells, or in severe cases a blood transfusion.
Can Rh incompatibility be prevented?
Early prenatal care and treatment help prevent issues with Rh incompatibility.
Source: MedlinePlus, U.S. National Library of Medicine. MedlinePlus topic page. Topic date: 11/01/2011. MedlinePlus file date: 10/15/2026 02:30:37.
This information is educational and is not medical advice.