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About Duodenal Ulcer

A duodenal ulcer is an open sore that develops on the lining of the duodenum, the first part of your small intestine. These can cause significant discomfort, but effective treatments are available. TheDrugClub is dedicated to helping you afford the necessary medications, ensuring your path to relief is accessible and budget-friendly.

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

MedlinePlus overview of Duodenal Ulcer

A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain:

Starts between meals or during the night

Briefly stops if you eat or take antacids

Lasts for minutes to hours

Comes and goes for several days or weeks

Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse.

To see if you have an H. pylori infection, your doctor will test your blood, breath, or stool. Your doctor also may look inside your stomach and duodenum by doing an endoscopy or x-ray.

Peptic ulcers will get worse if not treated. Treatment may include medicines to reduce stomach acids or antibiotics to kill H. pylori. Antacids and milk can't heal peptic ulcers. Not smoking and avoiding alcohol can help. You may need surgery if your ulcers don't heal.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Source: MedlinePlus, U.S. National Library of Medicine. MedlinePlus topic page. Topic date: 02/19/1999. MedlinePlus file date: 10/15/2026 02:30:37.

This information is educational and is not medical advice.

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