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Premenstrual Syndrome Medications, Costs & Savings

Pharmacist insight

For hormonal medications, timing consistency is crucial for optimal effectiveness. I recommend setting a daily alarm as a reminder. Many generic oral contraceptives and hormone replacement therapies are bioequivalent to brand-name versions, offering the same protection at lower cost.

Angela C. Beverly, PharmD

About Premenstrual Syndrome

Premenstrual Syndrome (PMS) affects millions, bringing a range of physical and emotional symptoms each month. While common, its impact can be significant. The good news is that effective treatments exist, and TheDrugClub is here to help make these essential medications more affordable, easing the financial burden of managing PMS.

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

MedlinePlus overview of Premenstrual Syndrome

What is premenstrual syndrome (PMS)?

Premenstrual syndrome, or PMS, is a group of physical and emotional symptoms that start one to two weeks before your period. Most women have at least some symptoms of PMS, and the symptoms go away after their periods start. The symptoms may range from mild to severe.

What is premenstrual dysphoric disorder (PMDD)?

Premenstrual dysphoric disorder (PMDD) is a severe type of PMS. With PMDD, the symptoms are severe enough to interfere with your life. PMDD much less common than PMS.

What causes premenstrual syndrome (PMS)?

Researchers don't know exactly what causes PMS. Changes in hormone levels during the menstrual cycle may play a role. These changing hormone levels may affect some women more than others.

What are the symptoms of premenstrual syndrome (PMS)?

PMS symptoms are different for everyone. You may get physical symptoms, emotional symptoms, or both. Your symptoms may also change throughout your life.

Physical symptoms may include:

Breast swelling and tenderness

Acne

Bloating and weight gain

Headache

Joint pain

Backache

Constipation or diarrhea

Food cravings

Emotional symptoms may include:

Irritability

Mood swings

Crying spells

Depression

Anxiety

Sleeping too much or too little

Trouble with concentration and memory

Less interest in sex

How is premenstrual syndrome (PMS) diagnosed?

You may wish to see your health care provider if your symptoms bother you or affect your daily life.

There is no single test for PMS. Your provider will talk with you about your symptoms, including when they happen and how much they affect your life. To be diagnosed with PMS, your symptoms must:

Happen in the five days before your period for at least three menstrual cycles in a row

End within four days after your period starts

Keep you from enjoying or doing some of your normal activities

Your provider may wish to do tests to rule out other conditions which may cause similar symptoms.

What are the treatments for premenstrual syndrome (PMS)?

No single PMS treatment works for everyone. If your symptoms are not severe, you may be able to manage them with:

Over-the-counter pain relievers such as ibuprofen, aspirin, or naproxen, to help ease cramps, headaches, backaches, and breast tenderness

Getting regular exercise

Getting enough sleep

Eating healthy foods

Avoiding salt, caffeine, sugar, and alcohol in the two weeks before your period

Some studies have shown that certain vitamins may help with some symptoms of PMS. They include calcium and vitamin B6.

Some women take certain herbal supplements for PMS symptoms. But there is not enough evidence to prove that supplements are effective for PMS. Check with your provider before taking any vitamins or supplements.

If you are not able to manage your PMS symptoms, your provider may suggest prescription medicines. These medicines may also be used to treat PMDD. They include:

Hormonal birth control, which may help with the physical symptoms of PMS. But sometimes they may make the emotional symptoms worse. You may need to try several different types of birth control before you find the right one.

Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), which may help with emotional symptoms.

Diuretics ("water pills") to reduce symptoms of bloating and breast tenderness.

Anti-anxiety medicine to ease symptoms of anxiety.

Dept. of Health and Human Services Office on Women's Health

Source: MedlinePlus, U.S. National Library of Medicine. MedlinePlus topic page. Topic date: 03/10/2004. MedlinePlus file date: 10/15/2026 02:30:37.

This information is educational and is not medical advice.

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