Allopurinol — Membership Pricing

Related medications

Other medications associated with the same conditions in this catalog.

Also listed for Gout

• Colchicine
• Febuxostat
• Indomethacin
• Prednisone

Also listed for Gout (Hyperuricemia)

• Colchicine 0.6 mg tabs
• Indomethacin 25/50 mg caps

Other medications in Musculoskeletal

• Celecoxib
• Diclofenac
• Ibandronate
• Meloxicam
• Naproxen
• Raloxifene
• Risedronate
• Acetaminophen

About Allopurinol

Allopurinol is a widely prescribed medication known for effectively managing conditions like gout and certain kidney stones. For those struggling with high uric acid levels, it offers significant relief by preventing painful flare-ups. Allopurinol is a cornerstone medication for individuals facing chronic conditions related to high uric acid levels in the body. Its primary role is to prevent painful and debilitating symptoms, allowing patients to maintain a better quality of life. ### What Allopurinol Treats

The most common use for allopurinol is the long-term management of gout. Gout is a type of inflammatory arthritis caused by the accumulation of uric acid crystals in the joints, leading to sudden, severe attacks of pain, swelling, redness, and tenderness. Allopurinol doesn't treat acute gout attacks directly but works to prevent future episodes by lowering uric acid levels. It's also prescribed to prevent uric acid kidney stones in individuals prone to their formation. Furthermore, allopurinol is used to reduce high uric acid levels that can occur as a side effect of certain cancer treatments (a condition known as tumor lysis syndrome), which can otherwise lead to kidney damage. ### How Allopurinol Works

At its core, allopurinol is a xanthine oxidase inhibitor. Xanthine oxidase is an enzyme in the body responsible for converting purines (natural substances found in our bodies and in certain foods) into uric acid. By blocking this enzyme, allopurinol effectively reduces the production of uric acid, leading to lower levels in the blood and urine. This reduction helps prevent the formation of uric acid crystals in the joints, kidneys, and other tissues, thereby mitigating the symptoms of gout and the risk of kidney stones. ### Typical Costs of Allopurinol

As a widely available generic medication, allopurinol is generally considered affordable compared to many brand-name drugs. However, costs can still vary significantly depending on your pharmacy, dosage, and insurance coverage. Without insurance, a typical 30-day supply of generic allopurinol (e.g., 100mg or 300mg) might range anywhere from $10 to $50 or more. Even with insurance, co-pays can add up, especially for chronic conditions requiring long-term treatment. ### How TheDrugClub Members Save

This is where TheDrugClub makes a significant difference. For our valued members, accessing essential medications like allopurinol is not

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Allopurinol is approved for (FDA label)

Allopurinol tablets are indicated for: The management of adults with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy) The management of adult and pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels The management of adult patients with recurrent calcium oxalate calculi whose daily uric acid excretion exceeds 800 mg/day in male patients and 750 mg/day in female patients, despite lifestyle changes (such as reduction of dietary sodium, non-dairy animal protein, oxalate rich foods, refined sugars and increases in oral fluids and fruits and vegetables) Limitations of Use Allopurinol tablets are not recommended for the treatment of asymptomatic hyperuricemia.

Source: Read the full FDA label on DailyMed. Label effective date: September 10, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Dosage forms and strengths for Allopurinol (FDA label)

Allopurinol Tablets, USP are available containing 100 mg of allopurinol, USP. The 100 mg tablets are white, round, functionally scored tablets debossed with M to the left of the score and 31 to the right of the score on one side of the tablet and blank on the other side. Tablets: 100 mg functionally scored .

Source: FDA prescribing information (DailyMed). Set ID: 8f50e91e-66a7-4fd4-888a-9f1986aa661c. SPL document ID: 5b231ff5-2257-6463-e063-6294a90ab02b. Label effective date: September 10, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Allopurinol (FDA label)

The following clinically significant adverse reactions are described elsewhere in the labeling: Skin Rash and Hypersensitivity [see Warnings and Precautions (5.1) ] Nephrotoxicity [see Warnings and Precautions (5.3) ] Hepatoxicity [see Warnings and Precautions (5.4) ] Myelosuppression [see Warnings and Precautions (5.5) ] Potential Effect on Driving and Use of Machinery [see Warnings and Precautions (5.6) ] The following adverse reactions associated with the use of allopurinol tablets were identified in literature, unpublished clinical trials or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The most frequent adverse reaction to allopurinol tablets is skin rash. Most Common Adverse Reactions (≥ 1%) Gastrointestinal: Diarrhea, nausea, alkaline phosphatase increase, AST/ALT increase.

Source: FDA prescribing information (DailyMed). Set ID: 8f50e91e-66a7-4fd4-888a-9f1986aa661c. SPL document ID: 5b231ff5-2257-6463-e063-6294a90ab02b. Label effective date: September 10, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Allopurinol (FDA label)

Allopurinol tablets are contraindicated in patients with a history of hypersensitivity reaction to allopurinol or to any of the ingredients of allopurinol tablets. Known hypersensitivity to allopurinol or to any of the ingredients of allopurinol tablets .

Source: FDA prescribing information (DailyMed). Set ID: 8f50e91e-66a7-4fd4-888a-9f1986aa661c. SPL document ID: 5b231ff5-2257-6463-e063-6294a90ab02b. Label effective date: September 10, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Warnings and precautions for Allopurinol (FDA label)

Skin Rash and Hypersensitivity: Allopurinol has been associated with serious and sometimes fatal dermatological reactions. Discontinue allopurinol tablets at the first appearance of skin rash or other signs of hypersensitivity reaction. ( 5.1 ) Gout Flares: May occur during initiation of treatment. Concurrent prophylactic treatment with colchicine or anti-inflammatory agents is recommended. ( 5.2 ) Nephrotoxicity: Allopurinol may affect kidney function. Patients with decreased kidney function require lower doses of allopurinol tablets. ( 5.3 ) Hepatoxicity: Cases of reversible hepatotoxicity have occurred.

Source: FDA prescribing information (DailyMed). Set ID: 8f50e91e-66a7-4fd4-888a-9f1986aa661c. SPL document ID: 5b231ff5-2257-6463-e063-6294a90ab02b. Label effective date: September 10, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Drug interactions for Allopurinol (FDA label)

The following drugs may increase the risk of serious skin reactions: bendamustine, thiazide diuretics, ampicillin and amoxicillin. ( 7.1 ) Capecitabine: Avoid concomitant use. ( 7.2 ) Mercaptopurine or Azathioprine: Reduce mercaptopurine or azathioprine dose as recommended in the respective prescribing information. ( 7.2 ) Pegloticase: Discontinue and refrain from initiating treatment with allopurinol tablets. ( 7.2 ) See FPI for complete list of significant drug interactions. ( 7.2 ) 7.1 Drugs Known to Affect the Occurrence of Skin Rash and Hypersensitivity Concomitant use of the following drugs may increase the risk of skin rash, which may be severe: bendamustine, thiazide diuretics, ampicillin and amoxicillin.

Source: FDA prescribing information (DailyMed). Set ID: 8f50e91e-66a7-4fd4-888a-9f1986aa661c. SPL document ID: 5b231ff5-2257-6463-e063-6294a90ab02b. Label effective date: September 10, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.