Baclofen — $0 with Membership

Related medications

Other medications associated with the same conditions in this catalog.

Also listed for Muscle Spasm

• Cyclobenzaprine
• Tizanidine
• Cyclobenzaprine 5/10 mg tabs
• Tizanidine 2/4 mg tabs

Other medications in Pain & Inflammation

• Buprenorphine
• Buprenorphine-Naloxone
• Butorphanol
• Caffeine-Ergotamine
• Capsaicin
• Capsaicin Patch
• Carisoprodol
• Chlorzoxazone

About Baclofen

Baclofen is a widely prescribed medication used to alleviate severe muscle spasms and related discomfort. If you're managing conditions like multiple sclerosis or spinal cord injuries, baclofen can offer significant relief. At TheDrugClub, we believe essential medications should be accessible and affordable, which is why we're proud to offer baclofen to our members with incredible savings.

Baclofen is primarily used to treat spasticity, a condition characterized by stiff or rigid muscles, often accompanied by involuntary muscle contractions. This spasticity can be painful and debilitating, interfering with daily activities. It's commonly prescribed for individuals suffering from multiple sclerosis (MS), spinal cord injuries, cerebral palsy, and other neurological disorders that cause muscle stiffness and spasms. By reducing the frequency and severity of these spasms, baclofen helps improve muscle movement, reduce pain, and enhance overall quality of life.

Baclofen is a muscle relaxant that works by affecting the central nervous system. Its primary mechanism involves mimicking the action of gamma-aminobutyric acid (GABA), a natural neurotransmitter in the brain and spinal cord that inhibits nerve activity. Specifically, baclofen acts as an agonist at GABA-B receptors, leading to a reduction in the release of excitatory neurotransmitters. This inhibitory action decreases the excitability of nerve cells in the spinal cord, which in turn reduces the

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Baclofen is approved for (FDA label)

Baclofen tablets are useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. Patients should have reversible spasticity so that baclofen treatment will aid in restoring residual function. Baclofen tablets, USP may also be of some value in patients with spinal cord injuries and other spinal cord diseases. Baclofen tablets are not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders. The efficacy of baclofen in stroke, cerebral palsy, and Parkinson’s disease has not been established and, therefore, it is not recommended for these conditions.

Source: Read the full FDA label on DailyMed. Label effective date: September 9, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Baclofen (FDA label)

The most common is transient drowsiness (10 to 63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving baclofen compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5 to 15%), weakness (5 to 15%) and fatigue (2 to 4%). Others reported: Neuro psychiatric : Confusion (1 to 11%), headache (4 to 8%), insomnia (2 to 7%); and, rarely, euphoria, excitement, depression, hallucinations, paresthesia, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizure. Cardiovascular : Hypotension (0 to 9%). Rare instances of dyspnea, palpitation, chest pain, syncope.

Source: FDA prescribing information (DailyMed). Set ID: ab3760cd-a84b-49ba-88e3-b9ea73c55f82. SPL document ID: 5b0fd64a-ed61-0eae-e063-6394a90a2f99. Label effective date: September 9, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.