Bempedoic Acid — Discount Pricing

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About Bempedoic Acid

Bempedoic acid is an innovative medication offering a new approach to lowering "bad" LDL cholesterol, especially for those who struggle with traditional treatments. At TheDrugClub, we understand the importance of affordable healthcare. Explore how bempedoic acid can fit into your health plan, and discover significant savings available through your membership.

What is Bempedoic Acid and What Does It Treat?

Bempedoic acid is an oral medication primarily used to lower low-density lipoprotein cholesterol (LDL-C), often referred to as "bad" cholesterol. It's typically prescribed for adults with established atherosclerotic cardiovascular disease (ASCVD) or heterozygous familial hypercholesterolemia (HeFH) who require additional LDL-C lowering. This is particularly relevant for individuals who are unable to reach their cholesterol goals with maximally tolerated statin therapy, or for those who experience statin-related side effects.

How Does Bempedoic Acid Work?

Unlike statins, which inhibit an enzyme called HMG-CoA reductase, bempedoic acid works by inhibiting ATP citrate lyase (ACL) in the liver. This enzyme is involved in the cholesterol synthesis pathway, upstream from where statins act. By blocking ACL, bempedoic acid reduces the production of cholesterol in the liver. This reduction leads to an increased number of LDL receptors on the surface of liver cells, which in turn helps to remove more LDL-C from the bloodstream. This unique mechanism of action makes it a valuable option for patients who need complementary or alternative cholesterol-lowering strategies.

Typical Costs of Bempedoic Acid

As a newer, branded medication, bempedoic acid can carry a significant list price. Without insurance or discount programs, the typical monthly cost can range from several hundred dollars, varying based on the pharmacy, dosage, and your specific location. These costs can be a barrier for many patients, highlighting the importance of exploring all available savings options. Prices can fluctuate, so comparing costs across different pharmacies is always a wise step.

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The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Bempedoic Acid is approved for (FDA label)

NEXLETOL is indicated: to reduce the risk of major adverse cardiovascular events (cardiovascular death, myocardial infarction, stroke, or coronary revascularization) in adults at increased risk for these events who are unable to take recommended statin therapy (including those not taking a statin). as an adjunct to diet and exercise, in combination with other low-density lipoprotein cholesterol (LDL-C) lowering therapies, or alone when concomitant LDL-C lowering therapy is not possible, to reduce LDL-C in adults with hypercholesterolemia, including heterozygous familial hypercholesterolemia (HeFH).

Source: Read the full FDA label on DailyMed. Label effective date: June 25, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Dosage forms and strengths for Bempedoic Acid (FDA label)

NEXLETOL is available as: Tablets: 180 mg, white to off-white, oval shaped, debossed with "180" on one side and "ESP" on the other side. Tablets: 180 mg ( 3 )

Source: FDA prescribing information (DailyMed). Set ID: 88d06d89-a3da-40b4-b273-8f4f7d56c4c9. SPL document ID: e67aa4eb-b86f-4cc0-8a38-e8405de2a113. Label effective date: June 25, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Bempedoic Acid (FDA label)

The following clinically significant adverse reactions are described elsewhere in the labeling: Hyperuricemia [see Warnings and Precautions (5.1) ] Tendon Rupture [see Warnings and Precautions (5.2) ] Common adverse reactions in the ( 6.1 ): Primary hypercholesterolemia trials (incidence ≥ 2% and more frequent than placebo) were upper respiratory tract infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia, and elevated liver enzymes. Cardiovascular outcomes trial (incidence ≥ 2% and 0.5% greater than placebo) were hyperuricemia, renal impairment, anemia, elevated liver enzymes, muscle spasms, gout, and cholelithiasis.

Source: FDA prescribing information (DailyMed). Set ID: 88d06d89-a3da-40b4-b273-8f4f7d56c4c9. SPL document ID: e67aa4eb-b86f-4cc0-8a38-e8405de2a113. Label effective date: June 25, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Bempedoic Acid (FDA label)

NEXLETOL is contraindicated in patients with a prior serious hypersensitivity reaction to bempedoic acid or any of the excipients in NEXLETOL. Serious hypersensitivity reactions, such as angioedema, have occurred [see Adverse Reactions (6.2) ]. History of a serious hypersensitivity reaction to bempedoic acid or any of the excipients in NEXLETOL. ( 4 )

Source: FDA prescribing information (DailyMed). Set ID: 88d06d89-a3da-40b4-b273-8f4f7d56c4c9. SPL document ID: e67aa4eb-b86f-4cc0-8a38-e8405de2a113. Label effective date: June 25, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Warnings and precautions for Bempedoic Acid (FDA label)

Hyperuricemia: Elevations in serum uric acid have occurred. Assess uric acid levels periodically as clinically indicated. Monitor for signs and symptoms of hyperuricemia, and initiate treatment with urate-lowering drugs as appropriate. ( 5.1 ) Tendon Rupture: Tendon rupture has occurred. Discontinue NEXLETOL at the first sign of tendon rupture. Avoid NEXLETOL in patients who have a history of tendon disorders or tendon rupture. ( 5.2 ) 5.1 Hyperuricemia NEXLETOL inhibits renal tubular OAT2 and may increase blood uric acid levels [see Clinical Pharmacology (12.3) ] . In the primary hypercholesterolemia trials [see Clinical Studies (14.2) ] , 26% of NEXLETOL-treated patients with normal baseline uric acid values (versus 9.5% placebo) experienced hyperuricemia one or more times, and 3.5% of patients experienced clinically significant hyperuricemia reported as an adverse reaction (versus 1.1% placebo).

Source: FDA prescribing information (DailyMed). Set ID: 88d06d89-a3da-40b4-b273-8f4f7d56c4c9. SPL document ID: e67aa4eb-b86f-4cc0-8a38-e8405de2a113. Label effective date: June 25, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.