Flurbiprofen — Membership Pricing

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About Flurbiprofen

What is Flurbiprofen and What Does It Treat?

Flurbiprofen is a potent nonsteroidal anti-inflammatory drug (NSAID) used to manage a variety of pain and inflammatory conditions. It's often prescribed for the signs and symptoms of rheumatoid arthritis and osteoarthritis, helping to reduce joint pain, stiffness, and swelling. Beyond chronic conditions, it can also be used for acute pain, such as that associated with menstrual cramps (dysmenorrhea) or other musculoskeletal injuries like tendinitis or bursitis. An ophthalmic (eye drop) formulation of flurbiprofen is also available, specifically used to prevent miosis (pupil constriction) during certain eye surgeries, such as cataract extraction.

How Does Flurbiprofen Work?

Like other NSAIDs, flurbiprofen works by inhibiting the production of prostaglandins, which are natural substances in the body that play a key role in mediating pain, inflammation, and fever. By blocking the enzymes (cyclooxygenases, or COX-1 and COX-2) responsible for prostaglandin synthesis, flurbiprofen effectively reduces the inflammatory response, thereby alleviating pain and swelling. This mechanism of action makes it a valuable tool in managing conditions where inflammation is a primary component of discomfort.

Understanding Typical Costs

The cost of flurbiprofen can vary significantly depending on factors such as dosage, quantity, whether it's a generic or brand-name product, and the pharmacy you choose. Without insurance, a

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Flurbiprofen is approved for (FDA label)

Flurbiprofen tablets are indicated: For relief of the signs and symptoms of rheumatoid arthritis. For relief of the signs and symptoms of osteoarthritis. Flurbiprofen tablets are a nonsteroidal anti-inflammatory drug indicated for Relief of the signs and symptoms of rheumatoid arthritis ( 1 ) Relief of the signs and symptoms of osteoarthritis ( 1 )

Source: Read the full FDA label on DailyMed. Label effective date: February 3, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Boxed warning for Flurbiprofen (FDA label)

WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS See full prescribing information for complete boxed warning. Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use ( 5.1 ) Flurbiprofen tablets are contraindicated in the setting of coronary artery bypass graft (CABG) surgery ( 4 , 5.1 ) NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events ( 5.2 ) Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal.

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Dosage forms and strengths for Flurbiprofen (FDA label)

Flurbiprofen Tablets, USP: 100 mg round, convex, blue, film-coated tablets debossed "NH" and "100" Tablets: 100 mg ( 3 )

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Flurbiprofen (FDA label)

The following adverse reactions are discussed in greater detail in other sections of the labeling: Cardiovascular Thrombotic Events [ see Warnings and Precautions (5.1) ] GI Bleeding, Ulceration and Perforation [ see Warnings and Precautions (5.2) ] Hepatotoxicity [ see Warnings and Precautions (5.3) ] Hypertension [ see Warnings and Precautions (5.4) ] Heart Failure and Edema [ see Warnings and Precautions (5.5) ] Renal Toxicity and Hyperkalemia [ see Warnings and Precautions (5.6) ] Anaphylactic Reactions [ see Warnings and Precautions (5.7) ] Serious Skin Reactions [ see Warnings and Precautions (5.9) ] Hematologic Toxicity [ see Warnings and Precautions (5.12) ] Most common adverse reactions (incidence > 3% from clinical trials) are: abdominal pain, dyspepsia, nausea, diarrhea, constipation, headache, edema, signs and symptoms suggesting urinary tract infection ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Allucent at 1-866-511-6754 or FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch for voluntary reporting of adverse reactions. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Flurbiprofen (FDA label)

Flurbiprofen tablets are contraindicated in the following patients: Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to flurbiprofen or any components of the drug product [ see Warnings and Precautions (5.7 , 5.9) ] History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, sometimes fatal, anaphylactic reactions to nonsteroidal anti-inflammatory drugs have been reported in such patients [ see Warnings and Precautions (5.7 , 5.8) ]. In the setting of coronary artery bypass graft (CABG) surgery [ see Warnings and Precautions (5.1) ]. Known hypersensitivity to flurbiprofen or any components of the drug product ( 5.7 , 5.9 ) History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs ( 5.7 , 5.8 ) In the setting of CABG surgery ( 5.1 )

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Warnings and precautions for Flurbiprofen (FDA label)

Hepatotoxicity : Inform patients of warning signs and symptoms of hepatotoxicity. Discontinue if abnormal liver tests persist or worsen or if clinical signs and symptoms of liver disease develop ( 5.3 ) Hypertension : Patients taking some antihypertensive medications may have impaired response to these therapies when taking NSAIDs. Monitor blood pressure ( 5.4 , 7 ) Heart Failure and Edema : Avoid use of flurbiprofen in patients with severe heart failure unless benefits are expected to outweigh risk of worsening heart failure (5.5) Renal Toxicity : Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia.

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Drug interactions for Flurbiprofen (FDA label)

See Table 1 for clinically significant drug interactions with flurbiprofen. Table 1: Clinically Significant Drug Interactions with Flurbiprofen Drugs That Interfere with Hemostasis Clinical Impact: Flurbiprofen and anticoagulants such as warfarin have a synergistic effect on bleeding. The concomitant use of flurbiprofen and anticoagulants have an increased risk of serious bleeding compared to the use of either drug alone. Serotonin release by platelets plays an important role in hemostasis. Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone.

Source: FDA prescribing information (DailyMed). Set ID: 4670cf21-eb0e-4f5a-ab22-41af85733525. SPL document ID: d3fa269f-43c4-4862-b4d2-ec5b04d050c8. Label effective date: February 3, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.