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Lubiprostone — Discount Pricing

Lubiprostone is not confirmed for no-additional-cost pricing. Discount pricing may be available; confirm the price with the dispensing pharmacy.

Lubiprostone Pricing

Pricing typePrice
TheDrugClubDiscount pricing may be available
Typical Retail$191.00

Discount pricing may be available; confirm the price with the dispensing pharmacy.

About Lubiprostone

Lubiprostone is a prescription medication. Ask your doctor if Lubiprostone is right for you.

How to Check Lubiprostone Pricing

  1. Join TheDrugClub for $19.95/month
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  3. Present your card at a participating pharmacy
  4. Check active-formulary eligibility or available discount pricing

Lubiprostone at Participating Pharmacies

Pharmacy participation and fulfillment options vary. Present your membership card and confirm current pricing before filling.

Other medications in Digestive Health

About Lubiprostone

Lubiprostone is a prescription medication used to alleviate symptoms of certain chronic constipation conditions. For those managing persistent digestive issues, understanding your treatment options is key. At TheDrugClub, we believe in making essential medications like lubiprostone more accessible and affordable. Discover how our membership can help you save on your prescription.

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Lubiprostone is approved for (FDA label)

Lubiprostone is a chloride channel activator indicated for the treatment of: chronic idiopathic constipation (CIC) in adults. ( 1.1 ) opioid-induced constipation (OIC) in adult patients with chronic, non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation. ( 1.2 ) Limitations of Use: Effectiveness of lubiprostone in the treatment of OIC in patients taking diphenylheptane opioids (e.g., methadone) has not been established. ( 1.2 , 7.1 ) irritable bowel syndrome with constipation (IBS-C) in women ≥ 18 years old. ( 1.3 ) 1.1 Chronic Idiopathic Constipation in Adults Lubiprostone is indicated for the treatment of chronic idiopathic constipation (CIC) in adults. 1.2 Opioid-Induced Constipation in Adult Patients with Chronic Non-Cancer Pain Lubiprostone is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.

Source: Read the full FDA label on DailyMed. Label effective date: July 28, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Dosage forms and strengths for Lubiprostone (FDA label)

Lubiprostone is available as an oval, gelatin capsule containing 8 mcg or 24 mcg of lubiprostone. 8 mcg capsules are pink and are printed with "SPI" on one side 24 mcg capsules are orange and are printed with "SPI" on one side Capsules: 8 mcg and 24 mcg ( 3 )

Source: FDA prescribing information (DailyMed). Set ID: f4d506e0-1322-4fc4-e053-2995a90ac880. SPL document ID: 57b2423d-ecf1-abe5-e063-6394a90ad2a6. Label effective date: July 28, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Lubiprostone (FDA label)

The following adverse reactions are described below and elsewhere in labeling: Nausea [see Warnings and Precautions (5.1) ] Diarrhea [see Warnings and Precautions (5.2) ] Syncope and Hypotension [see Warnings and Precautions (5.3) ] Dyspnea [see Warnings and Precautions (5.4) ] Most common adverse reactions (> 4%) are: CIC: nausea, diarrhea, headache, abdominal pain, abdominal distension, and flatulence. ( 6.1 ) OIC: nausea and diarrhea. ( 6.1 ) IBS-C: nausea, diarrhea, and abdominal pain. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Sun Pharmaceutical Industries, Inc. at 1-800-406-7984 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Source: FDA prescribing information (DailyMed). Set ID: f4d506e0-1322-4fc4-e053-2995a90ac880. SPL document ID: 57b2423d-ecf1-abe5-e063-6394a90ad2a6. Label effective date: July 28, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

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