Metformin 500/850/1000 mg tabs — $0 with Membership

Related medications

Other medications associated with the same conditions in this catalog.

Also listed for Polycystic Ovary Syndrome (PCOS) – Symptom Control

• Combined oral contraceptives (various)

Also listed for Type 2 Diabetes Mellitus

• Canagliflozin
• Dapagliflozin
• Dulaglutide
• Empagliflozin
• Glimepiride
• Glipizide
• Insulin Glargine

About Metformin 500/850/1000 mg tabs

Metformin is a cornerstone medication for managing Type 2 Diabetes, helping millions effectively control their blood sugar. While it's a widely prescribed and generally affordable generic, costs can still add up. TheDrugClub is dedicated to making essential medications like metformin accessible, offering significant savings, including a $0 co-pay for our members.

Metformin, often available in 500mg, 850mg, and 1000mg tablets, is a first-line treatment for Type 2 Diabetes, a chronic condition where the body either doesn't produce enough insulin or doesn't use insulin effectively, leading to high blood sugar levels. Beyond its primary role in diabetes management, metformin is sometimes prescribed off-label for conditions like Polycystic Ovary Syndrome (PCOS).

How Metformin Works to Control Blood Sugar

Metformin belongs to a class of drugs called biguanides. Unlike some other diabetes medications that stimulate insulin production, metformin works primarily in three key ways:

1. Decreases Glucose Production: It reduces the amount of glucose (sugar) your liver releases into your bloodstream. 2. Reduces Glucose Absorption: It lessens the amount of glucose your intestines absorb from the food you eat. 3. Increases Insulin Sensitivity: It makes your body's cells more responsive to insulin, allowing them to take up glucose more effectively from the blood.

These actions collectively help to lower and stabilize blood sugar levels without typically causing hypoglycemia (low blood sugar) when used alone, making it a well-tolerated option for many.

Understanding Typical Metformin Costs

As a generic medication, metformin is generally more affordable than its brand-name counterparts. However, the cost can still vary widely depending on your specific dosage, the pharmacy you use, and your insurance plan's coverage, including deductibles and co-pays. Without insurance, or with a high-deductible plan, a month's supply of metformin might range from $4 to $30 or more. These costs, though seemingly small, can accumulate over time, creating a financial burden for individuals managing a chronic condition.

TheDrugClub: Your Path to $0 Co-Pay Metformin with Free Home Delivery

At TheDrugClub, we believe that managing your health shouldn't break the bank. That's why our membership program is designed to provide unprecedented access to essential medications like metformin. As a member, you can get your metformin 500mg,

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Metformin 500/850/1000 mg tabs is approved for (FDA label)

Metformin hydrochloride tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. Metformin hydrochloride tablets are a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

Source: Read the full FDA label on DailyMed. Label effective date: September 2, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Boxed warning for Metformin 500/850/1000 mg tabs (FDA label)

WARNING: LACTIC ACIDOSIS Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset of metformin-associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Metformin-associated lactic acidosis was characterized by elevated blood lactate levels (>5 mmol/Liter), anion gap acidosis (without evidence of ketonuria or ketonemia), an increased lactate/pyruvate ratio; and metformin plasma levels generally >5 mcg/mL [see Warnings and Precautions ( 5.1 ) ]. Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g. carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, and hepatic impairment. Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high risk groups are provided [see Dosage and Administration ( 2.3 ) , ( 2.7 ), Contraindications ( 4 ) , Warnings and Precautions ( 5.1) ]. If metformin-associated lactic acidosis is suspected, immediately discontinue metformin hydrochloride tablets and institute general supportive measures in a hospital setting. Prompt hemodialysis is recommended [see Warnings and Precautions ( 5.1 ) ]. WARNING: LACTIC ACIDOSIS See full prescribing information for complete boxed warning. • Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias.

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Dosage forms and strengths for Metformin 500/850/1000 mg tabs (FDA label)

Metformin hydrochloride tablets, USP is available as: • 500 mg Tablets : White to off-white, round, film-coated tablets free from physical defects, debossed with “M24” on one side and “500” on the other side. • 850 mg Tablets : White to off-white, round, film-coated tablets free from physical defects, debossed with “M25” on one side and “850” on the other side. • 1,000 mg Tablets : White to off-white, oval, biconvex, film-coated tablets free from physical defects, debossed with “M26” on one side and “1000” on the other side and with a bisect line on both sides. • Metformin Hydrochloride Tablets, USP: 500 mg, 850 mg, and 1,000 mg

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Metformin 500/850/1000 mg tabs (FDA label)

The following adverse reactions are also discussed elsewhere in the labeling: • Lactic Acidosis [see Boxed Warning and Warnings and Precautions ( 5.1 )] • Vitamin B 12 Deficiency [see Warnings and Precautions ( 5.2 )] • Hypoglycemia [see Warnings and Precautions ( 5.3 )] For metformin hydrochloride tablets, the most common adverse reactions (>5.0%) are diarrhea, nausea/vomiting, flatulence, asthenia, indigestion, abdominal discomfort, and headache. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Ascend Laboratories, LLC at 1-877-272-7901 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Studies Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Metformin 500/850/1000 mg tabs (FDA label)

Metformin hydrochloride tablets are contraindicated in patients with: • Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) [see Warnings and Precautions ( 5.1 ) ]. • Hypersensitivity to metformin. • Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. • Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) ( 4 , 5.1 ) • Hypersensitivity to metformin ( 4 ) • Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. ( 4 )

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Warnings and precautions for Metformin 500/850/1000 mg tabs (FDA label)

• Lactic Acidosis: See boxed warning. ( 5.1 ) • Vitamin B 12 Deficiency: Metformin may lower vitamin B 12 levels. Measure hematological parameters annually and vitamin B 12 at 2 to 3 year intervals and manage any abnormalities. ( 5.2 ) • Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues: Increased risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. Lower dose of insulin or insulin secretagogue may be required ( 5.3 ) 5.1 Lactic Acidosis There have been post marketing cases of metformin-associated lactic acidosis, including fatal cases. These cases had a subtle onset and were accompanied by nonspecific symptoms such as malaise, myalgias, abdominal pain, respiratory distress, or increased somnolence; however, hypotension and resistant bradyarrhythmias have occurred with severe acidosis.

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Drug interactions for Metformin 500/850/1000 mg tabs (FDA label)

Table 2 presents clinically significant drug interactions with metformin hydrochloride tablets. Table 2: Clinically Significant Drug Interactions with Metformin Hydrochloride Tablets Carbonic Anhydrase Inhibitors Clinical Impact: Carbonic anhydrase inhibitors frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Concomitant use of these drugs with metformin hydrochloride may increase the risk for lactic acidosis. Intervention: Consider more frequent monitoring of these patients. Examples: Topiramate, zonisamide, acetazolamide or dichlorphenamide. Drugs that Reduce Metformin Hydrochloride Clearance Clinical Impact: Concomitant use of drugs that interfere with common renal tubular transport systems involved in the renal elimination of metformin (e.g., organic cationic transporter-2 [OCT2] / multidrug and toxin extrusion [MATE] inhibitors) could increase systemic exposure to metformin and may increase the risk for lactic acidosis [ see Clinical Pharmacology ( 12.3 ) ]. Intervention: Consider the benefits and risks of concomitant use with metformin hydrochloride.

Source: FDA prescribing information (DailyMed). Set ID: b6d7edc9-93d6-4480-906d-55c18d053600. SPL document ID: 017fc887-de17-4f26-a715-b28bc6271e09. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.