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Tolvaptan — Discount Pricing

Tolvaptan is not confirmed for no-additional-cost pricing. Discount pricing may be available; confirm the price with the dispensing pharmacy.

Tolvaptan Pricing

Pricing typePrice
TheDrugClubDiscount pricing may be available
Typical Retail$43.00

Discount pricing may be available; confirm the price with the dispensing pharmacy.

About Tolvaptan

Tolvaptan is a prescription medication. Ask your doctor if Tolvaptan is right for you.

How to Check Tolvaptan Pricing

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Tolvaptan at Participating Pharmacies

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Other medications in Diabetes & Metabolism

About Tolvaptan

Tolvaptan is a medication with distinct applications, primarily known for its role in managing fluid balance and certain kidney conditions. It is specifically approved to treat clinically significant euvolemic and hypervolemic hyponatremia (low sodium levels in the blood) in adults, particularly those associated with conditions like heart failure, cirrhosis, or Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Beyond hyponatremia, tolvaptan also plays a crucial role in slowing the progression of cyst growth in Autosomal Dominant Polycystic Kidney Disease (ADPKD).

How Tolvaptan Works

Tolvaptan is classified as a selective vasopressin V2-receptor antagonist. In simpler terms, it works by blocking the action of vasopressin (also known as antidiuretic hormone) in the kidneys. This blockade prevents the kidneys from reabsorbing too much water, leading to an increase in water excretion without a significant loss of electrolytes like sodium. For patients with hyponatremia, this helps to raise serum sodium levels by removing excess water from the body. In ADPKD, by inhibiting the V2 receptors, tolvaptan is thought to reduce the proliferation of renal tubular epithelial cells and fluid secretion into cysts, thereby slowing the enlargement of kidney cysts and preserving kidney function.

Typical Costs of Tolvaptan

Tolvaptan is a high-cost medication, reflecting its specialized nature and the conditions it treats. Without insurance or significant discounts, the monthly cost for a typical prescription can range from several hundred to several thousand dollars, depending on the dosage, pharmacy, and specific formulation. This substantial expense can be a

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Tolvaptan is approved for (FDA label)

Tolvaptan tablet is indicated to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Tolvaptan tablet is a selective vasopressin V 2 -receptor antagonist indicated to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD) ( 1 )

Source: Read the full FDA label on DailyMed. Label effective date: August 26, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

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