Trimethoprim-Sulfamethoxazole — Discount Pricing

Other medications in Infections

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• Abacavir

About Trimethoprim-Sulfamethoxazole

Trimethoprim sulfamethoxazole (TMP-SMX) is a combination antibiotic used to treat a wide range of bacterial infections. Whether you're dealing with a urinary tract infection or respiratory illness, this medication has been a trusted choice for decades. TheDrugClub members can access their trimethoprim sulfamethoxazole prescriptions with $0 co-pay and enjoy free home delivery, making treatment more accessible and affordable.

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Trimethoprim-Sulfamethoxazole is approved for (FDA label)

To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim oral suspension and other antibacterial drugs, sulfamethoxazole and trimethoprim oral suspension should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Source: Read the full FDA label on DailyMed. Label effective date: September 2, 2026.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Trimethoprim-Sulfamethoxazole (FDA label)

The following adverse reactions associated with the use of sulfamethoxazole and trimethoprim were identified in clinical trials, postmarketing or published reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The most common adverse reactions are gastrointestinal disturbances (nausea, vomiting, anorexia) and allergic skin reactions (such as rash and urticaria).

Source: FDA prescribing information (DailyMed). Set ID: c6171b62-835c-465e-905e-97f70438186e. SPL document ID: fc2caf1b-56ae-49f5-be07-f9c706b6b77a. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Trimethoprim-Sulfamethoxazole (FDA label)

Sulfamethoxazole and trimethoprim is contraindicated in the following situations: • known hypersensitivity to trimethoprim or sulfonamides • history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides • documented megaloblastic anemia due to folate deficiency • pediatric patients less than 2 months of age • marked hepatic damage • severe renal insufficiency when renal function status cannot be monitored • concomitant administration with dofetilide (see PRECAUTIONS ).

Source: FDA prescribing information (DailyMed). Set ID: c6171b62-835c-465e-905e-97f70438186e. SPL document ID: fc2caf1b-56ae-49f5-be07-f9c706b6b77a. Label effective date: September 2, 2026. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.