Promethazine — $0 with Membership

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About Promethazine

Promethazine is a versatile medication commonly prescribed for nausea, allergies, and even sleep. Understanding its benefits and how to access it affordably is key. TheDrugClub makes managing your prescriptions easier and more economical, offering significant savings on essential medications like promethazine.

Promethazine is a highly effective medication primarily known for its ability to combat nausea and vomiting, making it a go-to for issues like morning sickness, motion sickness, or post-operative discomfort. Beyond gastric distress, it's also a powerful antihistamine, providing relief from allergy symptoms such as sneezing, runny nose, and itchy eyes or skin. Its sedative properties make it useful for short-term insomnia or as a mild sedative before medical procedures, helping to calm patients and reduce anxiety.

Promethazine belongs to a class of drugs called phenothiazine antihistamines. Its primary action involves blocking histamine H1 receptors in the brain and body. By doing so, it reduces the effects of histamine, which is responsible for many allergy symptoms. In the brain, this blocking action contributes to its anti-nausea

The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.

What Promethazine is approved for (FDA label)

Promethazine hydrochloride tablets, USP are useful for: Perennial and seasonal allergic rhinitis. Vasomotor rhinitis. Allergic conjunctivitis due to inhalant allergens and foods. Mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Amelioration of allergic reactions to blood or plasma. Dermographism. Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled. Preoperative, postoperative, or obstetric sedation. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Therapy adjunctive to meperidine or other analgesics for control of post-operative pain. Sedation in both children and adults, as well as relief of apprehension and production of light sleep from which the patient can be easily aroused.

Source: Read the full FDA label on DailyMed. Label effective date: October 8, 2022.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Adverse reactions for Promethazine (FDA label)

Central Nervous System Drowsiness is the most prominent CNS effect of this drug. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Hallucinations have also been reported. Cardiovascular — Increased or decreased blood pressure, tachycardia, bradycardia, faintness. Dermatologic — Dermatitis, photosensitivity, urticaria. Hematologic — Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. Gastrointestinal — Dry mouth, nausea, vomiting, jaundice. Respiratory — Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). (See WARNINGS - Respiratory Depression ). Other — Angioneurotic edema. Neuroleptic malignant syndrome (potentially fatal) has also been reported. (See WARNINGS - Neuroleptic Malignant Syndrome ).

Source: FDA prescribing information (DailyMed). Set ID: 4f681538-7ac4-484c-9e6d-b571d73b9e0b. SPL document ID: ea92baba-9184-5d68-e053-2a95a90a5e8f. Label effective date: October 8, 2022. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.

Contraindications for Promethazine (FDA label)

Promethazine hydrochloride tablets, USP are contraindicated for use in pediatric patients less than two years of age. Promethazine hydrochloride tablets, USP are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.

Source: FDA prescribing information (DailyMed). Set ID: 4f681538-7ac4-484c-9e6d-b571d73b9e0b. SPL document ID: ea92baba-9184-5d68-e053-2a95a90a5e8f. Label effective date: October 8, 2022. Read the full label.

Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.