Tramadol — $0 with Membership
Tramadol has an active canonical formulary match. No-additional-cost pricing is subject to its listed supply, quantity, fill, and fulfillment limits.
Tramadol Pricing
| Pricing type | Price |
|---|---|
| TheDrugClub | $0 with membership |
| Typical Retail | $95.00 |
Free with membership subject to the listed formulary limits.
About Tramadol
Tramadol is a prescription medication. Ask your doctor if Tramadol is right for you.
Other strengths and forms of Tramadol
Combination products containing Tramadol
Conditions Treated with Tramadol
How to Check Tramadol Pricing
- Join TheDrugClub for $19.95/month
- Receive your member card by email
- Present your card at a participating pharmacy
- Check active-formulary eligibility or available membership pricing
Tramadol at Participating Pharmacies
- CVS Pharmacy
- Walgreens
- Walmart Pharmacy
- Rite Aid
- Kroger Pharmacy
- Costco Pharmacy
- Albertsons
- Safeway
- Publix Pharmacy
- H-E-B Pharmacy
Pharmacy participation and fulfillment options vary. Present your membership card and confirm current pricing before filling.
Related medications
Other medications associated with the same conditions in this catalog.
Also listed for Acute Musculoskeletal Pain
Also listed for Chronic Pain
Other medications in Pain & Inflammation
About Tramadol
Dealing with moderate to moderately severe pain can significantly impact your daily life. Tramadol is a widely prescribed medication known for its effectiveness in managing such discomfort. At TheDrugClub, we believe essential medications like tramadol should be accessible and affordable. Our members can enjoy significant savings, including a $0 co-pay, on this vital pain reliever.
What is Tramadol and What Does It Treat?
Tramadol is a prescription medication primarily used to treat moderate to moderately severe pain in adults. This can include pain from conditions like osteoarthritis, fibromyalgia, nerve damage, or post-surgical recovery. It's often prescribed when other non-opioid pain relievers haven't provided sufficient relief, offering an effective option for individuals seeking to improve their quality of life and manage chronic or acute discomfort.
How Does Tramadol Work?
Tramadol has a unique dual mechanism of action, which sets it apart from some other pain medications. Firstly, it works as a weak opioid agonist, binding to mu-opioid receptors in the brain and spinal cord, which helps to block pain signals. Secondly, tramadol also inhibits the reuptake of norepinephrine and serotonin, two neurotransmitters that play a role in pain modulation. By increasing the levels of these neurotransmitters, tramadol enhances the body's natural pain-inhibiting pathways. This combined action provides potent pain relief, making it a valuable tool in pain management strategies. It's important to use tramadol exactly as prescribed by your doctor to ensure safety and effectiveness.
Understanding Typical Costs of Tramadol
The cost of tramadol can
The information above is for educational purposes only and does not constitute medical advice. Consult your healthcare provider before making medication decisions.
What Tramadol is approved for (FDA label)
Tramadol hydrochloride tablets are indicated in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Source: Read the full FDA label on DailyMed. Label effective date: September 1, 2026.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Boxed warning for Tramadol (FDA label)
WARNING: SERIOUS AND LIFE-THREATENING RISKS FROM USE OF TRAMADOL HYDROCHLORIDE TABLETS ADDICTION, ABUSE AND MISUSE Because the use of tramadol hydrochloride tablets exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death, assess each patient’s risk prior to prescribing and reassess all patients regularly for the development of these behaviors and conditios [see Warnings and Precautions ( 5.1 ) ]. LIFE-THREATENING RESPIRATORY DEPRESSION Serious, life-threatening, or fatal respiratory depression may occur with use of tramadol hydrochloride tablets, especially during initiation or following a dose increase. To reduce the risk of respiratory depression, proper dosing and titration of tramadol hydrochloride tablets are essential [see Warnings and Precautions (5.2)]. ACCIDENTAL INGESTION Accidental ingestion of even one dose of tramadol hydrochloride tablets, especially by children, can result in a fatal overdose of tramadol [see Warnings and Precautions (5.2) ]. RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CN risk of NOWS, which may be lifethreatening if not recognized and treated.
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Dosage forms and strengths for Tramadol (FDA label)
Tramadol Hydrochloride Tablets USP, 50 mg are supplied as white film coated capsule shaped unscored tablets debossed with "ET50" on one side and plain on the other side. Tablets: 50 mg (3).
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Adverse reactions for Tramadol (FDA label)
The following serious adverse reactions are described, or described in greater detail, in other sections: Addiction, Abuse, and Misuse [see Warnings and Precautions (5.1)] Life-Threatening Respiratory Depression [see Warnings and Precautions (5.2)] Interactions with Benzodiazepines or Other CNS Depressants [see Warnings and Precautions (5.3)] Neonatal Opioid Withdrawal Syndrome [see Warnings and Precautions (5.4)] Ultra-Rapid Metabolism and Other Risk Factors for Life-threatening Respiratory Depression in Children [see Warnings and Precautions (5.6)] Opioid-Induced Hyperalgesia and Allodynia [see Warnings and Precautions (5.8)] Serotonin Syndrome [see Warnings and Precautions (5.9)] Seizures [see Warnings and Precautions (5.10)] Suicide [see Warnings and Precautions (5.11)] Adrenal Insufficiency [see Warnings and Precautions (5.13)] Severe Hypotension [see Warnings and Precautions (5.14)] Gastrointestinal Adverse Reactions [see Warnings and Precautions (5.16)] Hypersensitivity Reactions [see Warnings and Precautions (5.17)] Withdrawal [see Warnings and Precautions (5.18)] The most common incidence of treatment-emergent adverse events (≥15.0%) in patients from clinical trials were dizziness/vertigo, nausea, constipation, headache, somnolence, vomiting and pruritus (6) . To report SUSPECTED ADVERSE REACTIONS, ACI Healthcare USA, Inc. at 1-888-802-1213 or www.acihealthcareusa.com or FDA at 1-800-FDA-1088 orwww.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Contraindications for Tramadol (FDA label)
Tramadol hydrochloride tablets are contraindicated for: all children younger than 12 years of age [see Warnings and Precautions (5.6)] . post-operative management in children younger than 18 years of age following tonsillectomy and/or adenoidectomy [see Warnings and Precautions (5.6)]. Tramadol hydrochloride tablets are also contraindicated in patients with: Significant respiratory depression [see Warnings and Precautions (5.2)] . Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see Warnings and Precautions (5.12)] . Known or suspected gastrointestinal obstruction, including paralytic ileus [see Warnings and Precautions (5.16)] . Hypersensitivity to tramadol, any other component of this product or opioids [see Warnings and Precautions (5.17)] . Concurrent use of monoamine oxidase inhibitors (MAOIs) or use within the last 14 days [see Drug Interactions (7)]. Children younger than 12 years of age (4).
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Warnings and precautions for Tramadol (FDA label)
Opioid-Induced Hyperalgesia and Allodynia : Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain. If OIH carefully consider appropriately decreasing the dose of the current opioid analgesic, or opioid rotation ( 5.8 ) Serotonin Syndrome: May be life-threatening. Can occur with use of tramadol alone, with concomitant use of serotonergic drugs, with drugs that impair metabolism of serotonin or tramadol (5.8) . Risk of Seizure : Can occur at the recommended dose of tramadol. Concomitant use with other drugs may increase seizure risk.
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.
Drug interactions for Tramadol (FDA label)
Table 2: Clinically Significant Drug Interactions with Tramadol Hydrochloride Tablets Inhibitors of CYP2D6 Clinical Impact: The concomitant use of tramadol hydrochloride tablets and CYP2D6 inhibitors may result in an increase in the plasma concentration of tramadol and a decrease in the plasma concentration of M1, particularly when an inhibitor is added after a stable dose of tramadol hydrochloride tablets is achieved. Since M1 is a more potent µ-opioid agonist, decreased M1 exposure could result in decreased therapeutic effects, and may result in signs and symptoms of opioid withdrawal in patients who had developed physical dependence to tramadol. Increased tramadol exposure can result in increased or prolonged therapeutic effects and increased risk for serious adverse events including seizures and serotonin syndrome. After stopping a CYP2D6 inhibitor, as the effects of the inhibitor decline, the tramadol plasma concentration will decrease and the M1 plasma concentration will increase.
Source: FDA prescribing information (DailyMed). Set ID: c6104e62-5b2c-41a1-afb3-00dcf267a384. SPL document ID: 5a6ed8cc-52b6-62e9-e063-6294a90a15dc. Label effective date: September 1, 2026. Read the full label.
Excerpt from the FDA-approved prescribing information. This is not medical advice; talk to your doctor or pharmacist.